Crystal River s Newest Hotel for Business, Leisure and Eco-Travelers Welcome to the Holiday Inn Express Crystal River! Our modern, green friendly and smoke free hotel is located in the charming city of Crystal River, FL. Near the intersection of Hwy 19 and Hwy 44, the hotel is located East of Inverness, FL, North of Tampa, FL and West of Orlando, FL.Situated in Citrus County, Crystal River is a nature lover's dream and best known for having the world's highest concentration of manatees visiting the area's spring fed waters. The hotel is close to the Nature Coast s beautiful Eco-attractions that offer canoeing, kayaking, fishing, hiking or trail riding all available at Crystal River Preserve State Park. Visitors can take advantage of swimming, snorkeling or diving with manatees in Kings Springs or relaxing on Ft. Island Gulf Beach. The hotel is minutes from Progress Energy Nuclear Power Plant, Seven Rivers Regional Medical Center, Citrus Memorial Hospital and Simon Crystal River Mall. Enjoy premium amenities during your stay with us. Families will enjoy our spacious double king guest rooms with their choice of color theme. Business travelers can utilize our Crystal Meeting Room equipped with audio/visual equipment, accommodating up to 66 people. Be sure to check Crystal River, FL off of your list of the 1000 Places To See Before You Die. Our staff will make you feel so special, you won t want to leave!