The GuestHouse Inn St. Joseph is centrally located around all St. Joseph attractions in St. Joseph, MO including the Patee House Museum, Pony Express Museum, Jesse James home, and Missouri Western State University. Our property is conveniently located off Interstate 29 and offers complimentary parking. The GuestHouse Inn St. Joseph in St. Joseph, MO, hotel is near Kansas City International Airport and offers exceptional accommodations with our newly renovated rooms. We proudly serve complimentary hot continental breakfast each morning, and if you feel like being active, come swim in our seasonal outdoor heated pool or work out in our fitness center. Our hotel features complimentary Wi-Fi Internet access throughout the hotel, and handicapped-accessible rooms are available. Our 24-hour front-desk service is available for your convenience.