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Main Street Inn B&B

Traveller (30)
Room & Suite (5)
Dining (1)
221 N Main St, Sainte Genevieve, MO 63670-1339 See on map
Free Wifi
Free Parking
Breakfast included
Air Conditioning
Non-Smoking Hotel
Family Rooms
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Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been considered one of Missouri’s finest bed and breakfast establishments. Having recently undergone an extensive year-long ...More renovation, Proprietors, Susan O’Donnell and Patrick Fahey, along with Innkeeper, Jean Marie Rozier Sellberg, are thrilled to re-open the Main Street Inn B&B and provide a truly wonderful experience. Located in the heart of Sainte Genevieve’s Historic District, and surrounded by beautiful wine country, we are just a short one-hour drive from both St. Louis and Cape Girardeau, five hours from Chicago and just a little over four hours from Nashville. If you are looking for a relaxing and peaceful getaway, the Main Street Inn B&B is the perfect destination. Less
Hotel Amenities
Free Parking
Free High Speed Internet (WiFi)
Breakfast included
Air Conditioning
Non-Smoking Hotel
Room Service
Fitness Centre with Gym / Workout Room
Room types
Non-Smoking Rooms, Family Rooms
Room types
Non-Smoking Rooms, Family Rooms
Number of rooms
United States > Missouri > Sainte Genevieve
Nearby HotelsSee all 3 nearby hotels
Hotel Ste. Genevieve
22 reviews
.24 km away
Microtel Inn & Suites by Wyndham Sainte Genevieve
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Best Western Chester Hotel
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Red Bud Country Inn
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Nearby RestaurantsSee all 29 restaurants in Sainte Genevieve
Anvil Restaurant & Saloon
233 reviews
.40 km away
Audubon's Grill & Bar
152 reviews
.23 km away
Stella and Me
66 reviews
.03 km away
84 reviews
.33 km away
Nearby AttractionsSee all 28 attractions in Sainte Genevieve
Ste. Genevieve Welcome Center
61 reviews
.36 km away
Felix Valle House State Historic Site
39 reviews
.29 km away
Bolduc House Museum
44 reviews
.43 km away
Sainte Genevieve Catholic Parish
14 reviews
.47 km away
Traveller (30)
Room & Suite (5)
Dining (1)
Business Centre & Event Rooms (3)
Reviews (66)
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All reviewsthe main streetst louisbreakfast was excellenthouse is beautifulroom was spacioussecond floorporchhostsbooksperfection
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1 - 5 of 66 reviews
Reviewed 5 days ago via mobile

This was our second visit and my husband and I are sure to be regulars. This is beautifully updated, peaceful B&B with delicious food and engaging nightly wine and cheese socials. We love it here and are already looking forward to hearing back next year.

Thank Jcamille30
Reviewed 1 week ago

My husband and I had a great time in St. Genevieve. The Inn was remolded beautifully, the room was comfortable even down to the super soft toilet paper. The Inn keeper was very friendly shared lots of history about the down. Breakfast was delicious and...More

Thank Excursion714731
Reviewed 4 weeks ago via mobile

The 7 of us were traveling together and this was the second night of our 3 week road trip. What a fantastic experience!! We range in ages from 7 to 70 and all loved it. The rooms are beautiful, unique, and very comfortable and clean....More

Thank Escape745783
Reviewed 4 weeks ago via mobile

Beautiful hotel with amazing hospitality!! Delicious breakfast. Could not ask for a better place to stay. They provide you also with a cheese tray and wine for your stay. Would highly recommend. Quiet room and comfortable beds!

Thank Angela J
Reviewed 16 August 2018

We went to this B&B for our 25th Anniversary. Ste. Genevieve is a town incredibly rich in history and located in beautiful country. Jean was a great hostess and the breakfast was very good. We stayed in the rendezvous room with its own entrance, definitely...More

Thank Roger M
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Room Tips
"Stay up top for a better view or in the rendezvous or the room off of the porch"
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"We liked the Audubon room"
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"I looked at the rooms and everyone of them was beautiful."
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"make sure your floors don't squeek"
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