Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

Famed throughout Asia for its heady mix of eastern cultures, Penang Island is Malaysia’s prime melting pot. Roadside vendors serve some of the world’s best street food; its national parks offer white-sand beaches and wildlife; and UNESCO-listed George Town is full of colorful heritage houses.

The British colonial city of Ipoh had humble beginnings, but has blossomed into a beautiful cityscape that marries old-world charm with modern amenities. This is a foodie's city, offering endless street stalls and restaurants all eager to serve up a sample of mouthwatering local fare. Walk it all off on a jaunt through breathtaking limestone caves that seem carved by the capable hands of a higher power.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Vietnam's bustling largest city sets the cultural and economic pace for the country. The former Saigon boasts charming French colonial architecture and wide boulevards, usually thronged and choked with traffic. Taxis are an option for seeing the sprawling city. The War Remnants Museum shows the Vietnam War through Vietnamese eyes. Don't miss the impressive Jade Emperor Pagoda. Go to the frenetic Ben Thanh Market for food, flowers or frogs. Tour through the Mekong Delta, past rice paddies and houseboats.

Johor Bahru is the second-largest city in Malaysia and, with the opening of two major amusement parks in 2012, it is poised to become a major tourist destination. TripAdvisor travellers also recommend visiting the Arulmigu Sri Rajakaliamman Glass Temple, a unique Hindu temple decorated with brilliant glass mosaics.

Miri is a terrific base for exploring Borneo’s spectacular rainforests and alpine meadows. Here you’ll find four National Parks, each with its own distinct drawing power: Gunung Mulu is teeming with caves and limestone formations; Niah was the discovery site of prehistoric human remains; Lambir Hills features stunning waterfalls and wildlife; and Loagan Bunut is ideal for hiking and birdwatching.