Religious pilgrims have been travelling to Jerusalem for centuries, yet you don’t have to share their zeal in order to appreciate this city’s profound cultural and historical significance. Plan on seeing the major sights, but also leave plenty of time to walk through the streets and simply immerse yourself in the daily life of such an ancient and revered place.

A youthful, modern metropolis with a diverse population, Tel Aviv dates back to only 1909. Clubs, bars, a thriving arts community, gay life and beaches attract artists, musicians and young professionals to Tel Aviv's more secular scene. Its UNESCO-designated Bauhaus architecture has won the city the moniker "The White City". Walk, drive or take cabs between the cultural exhibition pavilions of Haaretz Museum, historic Independence Hall Museum, bustling Carmel Market and Old Jaffa's boardwalk.

With its postcard-worthy backdrop of golden sands, forested mountains, and miles of azure ocean, it’s no surprise that Fethiye is among the most-visited cruise ports on Turkey’s Turquoise Coast. The town itself is equally attractive, with leafy seafront promenades, lively bazaars, and ancient ruins.

Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

A visit to Pattaya is a wonderful way to explore the beaches along the Gulf of Thailand. Relaxed and family-friendly Jomtien Beach is a hot spot for watersports and seaside massages. The giant Buddha of Wat Khao Phra Bat keeps watch over the city, and the wooden Wang Boran Sanctuary of Truth pays homage to Buddhist and Hindu art and architecture. At night, tons of bars and strip clubs attract an adults-only crowd.

Phuket offers a rainbow spectrum of spectacular holiday sights from blue lagoons and pink sunsets to orange-robed monks. Three wheeled-Tuk Tuks, taxis, buses and long tailed boats transport visitors between these marvels. Phuket's south coast offers its most popular beaches. The north is more tranquil. Koh Phi Phi, Phang Nga Bay and Patong Beach are popular spots. Diving, snorkeling, wind surfing and sailing are just a few active options. Inland, forested hills, mountains and cliffs wait to be explored.

Forested hills, romantic white-sand beaches and crystal-clear waters greet visitors to tropical Palau Langkawi, the largest of the 99 islands in Langkawi archipelago. Known mysteriously as "Legendary Island" because of myths associated with its ancient geological formations, it drifts serenely alongside Malaysia in the azure Andaman Sea. Sample local cuisine at the night markets, hike to dramatic waterfalls or dive into an underwater marine park to take a guided glimpse at life beneath the sea.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Vietnam's bustling largest city sets the cultural and economic pace for the country. The former Saigon boasts charming French colonial architecture and wide boulevards, usually thronged and choked with traffic. Taxis are an option for seeing the sprawling city. The War Remnants Museum shows the Vietnam War through Vietnamese eyes. Don't miss the impressive Jade Emperor Pagoda. Go to the frenetic Ben Thanh Market for food, flowers or frogs. Tour through the Mekong Delta, past rice paddies and houseboats.