Southwest of London is Southampton (Soton to the locals), a metropolitan area centered around the port. However, tucked away on the side streets are ancient gems such as the Tudor House, Mottisfont Abbey, and "God's House," a museum located in a tower in the medieval wall. The ultra-modern Sea City Museum celebrates Southampton's seafaring past and the RMS Titanic. Looking for nightlife? Travelers can dance the hours away with bars, clubs, and live music, all accessible by public transportation.

Stroll Las Ramblas and enjoy Barcelona's unique blend of Catalan culture, distinctive architecture, lively nightlife and trendy, stylish hotels. You'll find Europe's best-preserved Gothic Quarter here, as well as amazing architectural works by Gaudi. La Sagrada Familia, considered Gaudi's masterpiece, is still under construction (your entrance fee helps to fund the project). Feel like a picnic? Look no further than the rambunctious La Boqueria market, where you can stock up on local delicacies.

The region of Campania curves around the bays of Naples and Sorrento, with towering Vesuvius and mountain ranges and massifs looming above. Ancient classical ruins are scattered throughout the region, from the ruins of Pompeii and Herculaneum to the Greek temples in Paestum. Popular resort towns include charming Sorrento and Amalfi, upscale Positano and haven for the elite, Ravello. For even more memorable sights, catch a ferry from Sorrento or Naples to the isle of Capri, home of the magical Blue Grotto.

Lisbon, the capital city of Portugal, has become an increasingly popular place to visit in recent years, with a warm Mediterranean climate in spite of its place facing the Atlantic Ocean. Full of bleached white limestone buildings and intimate alleyways, Lisbon's mix of traditional architecture and contemporary culture makes it the perfect place for a family holiday. Things to do in Lisbon: As Portugal's capital, there is a lot to see and do in Lisbon. Even exploring the city centre will take a few days out of a family holiday as there is no real central district, although Praça do Comércio is a good central place to start, in Baxia, or Rossio, the city's main square which has a sort of Trafalgar Square feel to it. Or you might try climbing up the Cristo Rei, a huge statue of Christ with spectacular views across the whole city. The Castelo de São Jorge also offers great views and isn't quite such a steep climb. A short tram ride to the west of Lisbon will also bring you to Belem, where you can explore attractions like the Belem Tower and the Belem Cultural Centre, which features a fantastic art collection including works by Dali, Picasso, Warhol and Magritte. In downtown Lisbon, you'll also want to visit the Gulbenkian, which has to be Portugal's answer to the British Museum full of fascinating cultural artifacts and with some superb gardens in the grounds. It's possible to have a fascinating educational family holiday in Lisbon, and there are also plenty of great beaches to work on your tan.

Iceland’s biggest city, Reykjavik bears the distinction of being the world’s northernmost capital, and for virtually every Icelandic visitor it serves as a gateway, just to the city itself or to the rugged adventure options beyond. Founded in the country’s southwest at the end of the 18th century, Reykjavik has been Iceland’s cultural hub ever since. These days, that culture includes a hip and internationally recognised music and arts scene, not to mention a notoriously wild nightlife.

Once known for smog, traffic and tacky architecture, Athens is a city reformed thanks to fortunes brought by the 2004 Summer Olympics. Spotless parks and streets, an ultra-modern metro, new motorways, an accessible airport and all signs in perfect English make the city easily negotiable. Meriting more than a stopover en route to the islands, sophisticated Athens sites include many pillars of Western history, from the Acropolis to the Temple of Olympian Zeus, as well as treasures in the National Archaeological Museum.

Over the centuries, many cultures have added their mark to this prized piece of land. Today, you can experience those influences firsthand by exploring Istanbul’s mahalles (neighbourhoods). From the holy sites of Sultanahmet and the 19th-century European elegance of Beyoğlu to the high fashion of Nişantaşı, the vibrant café society of Kadıköy and the football-loving streets of Beşiktaş, it’s easy to see why travellers say that Istanbul isn’t just one city, but many cities within one.

Funchal, the capital of the Madeira archipelago, was declared a city in the 1500s, and became an important point between the old and new worlds. The laid-back city owes much of its historical prominence to the white gold, the Madeiran sugar. Today Funchal is known for its appealing temperatures, wine and crafts. Top spots to visit include the open Worker's Market, Blandy's Wine Lodge and the Sacred Art Museum. Friendly locals, walkable streets and cheap taxis make the city easy to get around.

The sun-drenched Canary Islands lie close to North Africa and have an exotic flavour of their own. Hundreds of volcanoes, rolling sand dunes, rich forests and rugged cliffs dapple these seven Atlantic gems. Catch a ferry to Lanzarote. Ride a camel through volcanic Timanfaya National Park. Take on Tenerife, home of Mount Teide, Spain's tallest peak. Romp Grand Canary's beaches or hike La Gomera's Garajonay National Park. More adventures await on tiny El Hierro, verdant La Palma and peaceful Fuerteventura.

You've got to walk the Freedom Trail the first time you visit Boston. That's just a given. Make sure you step off the line on the pavement, though, and explore some of Boston's fine museums (try the Gardner—art masterpieces displayed in their collector's mansion) and old neighbourhoods (like the North End, where you can get the best cannoli this side of Italy). You can't claim to have experienced real Boston culture, though, unless you've watched a Red Sox game from the bleachers.