Famed throughout Asia for its heady mix of eastern cultures, Penang Island is Malaysia’s prime melting pot. Roadside vendors serve some of the world’s best street food; its national parks offer white-sand beaches and wildlife; and UNESCO-listed George Town is full of colorful heritage houses.

The beaches are a huge draw, but there’s so much more to do in this Malaysian hotspot. Frolic with the delicate residents of a butterfly farm, then explore the fragrant landscape of tropical spice garden and fruit farms. The massive collection of dolls, games and models at the Toy Museum brings joy to kids and kids at heart. Save some energy for the Night Market, a lively scene of stalls where good-natured bargaining skills come in handy.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Johor Bahru is the second-largest city in Malaysia and, with the opening of two major amusement parks in 2012, it is poised to become a major tourist destination. TripAdvisor travellers also recommend visiting the Arulmigu Sri Rajakaliamman Glass Temple, a unique Hindu temple decorated with brilliant glass mosaics.

Singapore is known as a bustling metropolis that also happens to be one of the cleanest and safest cities of its size in the world. (Just make sure you heed the local laws—something like spitting in the street might merely be considered rude in your hometown, but here, it carries a severe penalty.) You'll find historic sites like the Thian Hock Keng temple, superlative shopping (including gargantuan malls) and numerous beaches.

A visit to Pattaya is a wonderful way to explore the beaches along the Gulf of Thailand. Relaxed and family-friendly Jomtien Beach is a hot spot for watersports and seaside massages. The giant Buddha of Wat Khao Phra Bat keeps watch over the city, and the wooden Wang Boran Sanctuary of Truth pays homage to Buddhist and Hindu art and architecture. At night, tons of bars and strip clubs attract an adults-only crowd.

Nepal's capital is situated in a valley full of historic sites, ancient temples and shrines, golden pagodas and fascinating villages. Hotels, bars and restaurants cater to all budgets. Shops offer handicrafts, carpets and Nepali paper prints. Bus services, taxis and bicycles open up the city. Trek to see the Monkey Temple, the valley's oldest and most sacred shrine. Mingle with locals and animals amid Durbar Square's monuments and temples, or join mountain trekkers in the bustling Thamel District.

Laid out by British architect Edwin Lutyens, the Indian capital is a striking modern metropolis. A gracious contrast to Old Delhi's winding streets, the grand avenues and stately buildings of New Delhi are rich with history and culture, from Gandhi's Delhi home (and the site of his assassination) to the tomb of Humayun, a complex of Mughal buildings reminiscent of the Taj Mahal. Chaotic traffic is best left to the locals. Negotiate a good price for taxis or travel on the new Delhi Metro.

Shanghai is the cool, confident face of modern China, and its energy is infectious. Go to the Bund to watch ships on the river and marvel at the huge variety of architectural styles on display, or watch the crowds go by in People’s Square. Shoppers should make a beeline for the Fabric Market, where you can have a suit or dress tailor-made for you at bargain prices. At night, explore all manner of fashionable restaurants, bars and nightclubs or just stroll through the city enjoying the spectacular neon lights.

Thirteen hundred years ago, Nara (then Heiju-kyu) was the imperial capital of Japan. In 2010, festivities are in the works to celebrate this ancient city's anniversary. "Old Japan" is still easy to spot here, from Great Buddha Hall to traditional ryokans and the serene Isuien garden. travellers rave about walking tours of Nara, particularly in the historic Naramachi merchant area.