Famed throughout Asia for its heady mix of eastern cultures, Penang Island is Malaysia’s prime melting pot. Roadside vendors serve some of the world’s best street food; its national parks offer white-sand beaches and wildlife; and UNESCO-listed George Town is full of colorful heritage houses.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Nibble, slurp, and chow your way through Petaling Jaya, a suburb of Kuala Lumpur that offers up endless options for tourists hungry for a taste of local culture. The Wat Chetawan Thai Buddhist temple will offer you spiritual sustenance, while the thumping beats of hip nightlife spots will take you to a higher place.

Forested hills, romantic white-sand beaches and crystal-clear waters greet visitors to tropical Palau Langkawi, the largest of the 99 islands in Langkawi archipelago. Known mysteriously as "Legendary Island" because of myths associated with its ancient geological formations, it drifts serenely alongside Malaysia in the azure Andaman Sea. Sample local cuisine at the night markets, hike to dramatic waterfalls or dive into an underwater marine park to take a guided glimpse at life beneath the sea.

This charming city is a UNESCO world heritage site, with a rich trading history and multicultural heritage. Melaka is a rewarding town to explore and is about two hours from Kuala Lumpur.

Johor Bahru is the second-largest city in Malaysia and, with the opening of two major amusement parks in 2012, it is poised to become a major tourist destination. TripAdvisor travellers also recommend visiting the Arulmigu Sri Rajakaliamman Glass Temple, a unique Hindu temple decorated with brilliant glass mosaics.

Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

Kuching is a fine choice for an enriching vacation that's as packed with learning as it is leisure. Its many museums and impressive planetarium will enthrall even the tiniest travelers, and a quick climb to the top of the Kuching Civic Center will reward you with jaw-dropping 360-degree views. Grab a snack from a stall on the bustling waterfront, and don't miss the absolutely massive Sunday market, which is an electric experience for shoppers, vendors, and observers.

Kota Kinabalu on the island of Borneo is the bustling gateway to acclaimed Kinabalu National Park. The park's high point is 13,400-foot Mount Kinabula, Malaysia's tallest peak, a mecca for climbers. Ninety miles away, thrilling jungle trekking and camping await in the Crocker Range National Park.