A dense urban stopover where Thailand and Malaysia meet, Hat Yai exudes the international energy of a border hub. Though short on sights and historic charm, its shopping centres and floating market provide anything a modern traveller could ask for.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

Kuching is a fine choice for an enriching vacation that's as packed with learning as it is leisure. Its many museums and impressive planetarium will enthrall even the tiniest travelers, and a quick climb to the top of the Kuching Civic Center will reward you with jaw-dropping 360-degree views. Grab a snack from a stall on the bustling waterfront, and don't miss the absolutely massive Sunday market, which is an electric experience for shoppers, vendors, and observers.

Kota Kinabalu on the island of Borneo is the bustling gateway to acclaimed Kinabalu National Park. The park's high point is 13,400-foot Mount Kinabula, Malaysia's tallest peak, a mecca for climbers. Ninety miles away, thrilling jungle trekking and camping await in the Crocker Range National Park.

You can eat very well—and very cheaply—in Taipei. The restaurants may not look posh, but the quality of the food is superlative. And there’s a huge variety of restaurants—in addition to local Taiwanese specialties, you’ll find regional cuisines from all over China, as well as great Indian, Japanese and even Italian options. Just make sure to leave some room for snacks—street-vendor food here is addictive.

From modern skyscrapers and neon lights to Buddhist temples, palaces and pagodas, Seoul is a fascinating mix of old and new. A hub of business, culture and finance both within South Korea and internationally, Seoul houses the headquarters for some of the world's largest corporations. It also has one of the world's best subway systems – the easiest way to get around in this densely populated area. For the best view of the city, go to the tower on Namsan, one of the mountains that encircle the city.

Home to nearly nine million and powering an economy that exceeds both Hong Kong's and Thailand's, Osaka packs quite a punch. The confident, stylish city is a shopping hub, with fabulous restaurants and nightlife. It's an ideal base for exploring the Kansai region: Kyoto's World Heritage Sites, Nara's temple and Koya-san's eerie graves are within 90 minutes by train. Top city attractions include the aquarium, Osaka Castle, Universal Studios Japan and the futuristic Floating Garden Observatory.

Tradition collides with pop culture in Tokyo, where you can reverently wander ancient temples before rocking out at a karaoke bar. Wake up before the sun to catch the lively fish auction at the Toyosu Market, then refresh with a walk beneath the cherry blossom trees that line the Sumida River. Spend some time in the beautiful East Gardens of the Imperial Palace, then brush up on your Japanese history at the Edo-Tokyo Museum. Don’t forget to eat as much sushi, udon noodles, and wagashi (Japanese sweets) as your belly can handle.

Probably best known for its eponymous beer, Sapporo—the capital of Hokkaido, Japan’s northernmost island—has maintained the youthful and open atmosphere of the 1972 Olympic Winter Games, drawing international visitors for its annual Snow Festival and its world-famous ramen. Those seeking out the full diversity of Japanese cuisine will want to visit: a city with a ramen-inspired theme park is one that embraces and pampers foodies.