Giant anteaters, howler monkeys, ocelots, endangered jaguars and clouds of butterflies are among the attractions at this World Heritage-designated park that marks the border between Brazil and Argentina. By foot or by raft, explorers can view one of the world's most stunning waterfalls, Iguazu Falls. Among the park's 270 waterfalls, spectacular Devil's Throat combines 14 falls and generates a "perpetual rainbow" in good weather.

Punta del Este is known as the St. Tropez of Uruguay, thanks to its beautiful beaches, upscale resorts and swanky nightclubs. The Vegas-style Conrad Casino adds to the lively entertainment scene. For a break from surf and sand, saddle up with a local gaucho and ride horseback through the wild plains surrounding the city.

Six thousand years ago, human footprints were left in the volcanic mud along the shores of Lake Managua. Preserved over centuries, these footprints can be seen at The Museum of Acahualinca in Managua, the capital of Nicaragua. In addition to the footprints and impressive collections of pre-Colombian artifacts in the city's museums, Managua has much more to offer. The Tiscapa Lagoon Natural Reserve is a watery retreat within the city, with bars, shops, ziplines, and a canopy ride with views of downtown.

Lively nightclubs pulsing with Caribbean beats drive the nightlife scene of Cabarate, a breathtaking beach town. Not even the stubbornly two-left-footed can keep their toes from tapping when the sun goes down on Cabarete, which brims with culture and energy. Beachfront bars cum discotheques are the perfect spot to shake what your Mami gave you.