Stroll Las Ramblas and enjoy Barcelona's unique blend of Catalan culture, distinctive architecture, lively nightlife and trendy, stylish hotels. You'll find Europe's best-preserved Gothic Quarter here, as well as amazing architectural works by Gaudi. La Sagrada Familia, considered Gaudi's masterpiece, is still under construction (your entrance fee helps to fund the project). Feel like a picnic? Look no further than the rambunctious La Boqueria market, where you can stock up on local delicacies.

The Costa Dorada is one of the main tourist destinations on the Mediterranean. It is a rich and varied territory, with a long coastline bathed in sunshine and an interior dotted by quiet villages and cultivated fields. The Costa Dorada is much more than sun, sea and sand. It offers its visitors a wide range of leisure activities, culture, nature and history in an ideal setting of peace and tranquillity, perfect for holidays with the whole family.

From stylish Barcelona to sunny resort towns on the Costa Brava and Costa Dorada, Catalonia offers a wealth of attractions. Barcelona attracts those who love Gaudi's architecture, hot nightlife and thrilling restaurants. Elegant Tarragona's Roman ruins and amphitheater add to its historical appeal. Beach lovers flock to Mediterranean playgrounds including pine back-dropped Cape Salou, stunning Costa de Garraf, home to gay-popular beach resort Sitges, and the 40 sandy miles of La Maresme.

Salou, on the Costa Dorada, nestles between quaint Cambrils and calm La Pineda. Just seven miles south of elegant Tarragona, the compact resort town is a family favourite, due in no small part to the existence of Port Aventura and Aquopolis theme parks. Gentle beaches and a slew of exciting fiestas in August add to Salou's appeal for families.

Cambrils has a well-deserved reputation as the culinary capital of the Costa Dorada. There is a veritable cornucopia of fresh local ingredients, ranging from fish and other seafood to the internationally acclaimed DO Siurana olive oil. Between the historic population center and the ports, life in Cambrils unfurls peacefully around beaches and promenades. Looking on as fishing boats glide into the harbor and discovering the Old Quarter are two of the many pleasures that await in this Catalan town.

Tossa del Mar has beautiful beaches—and tourists flock to them in summer, so make sure you have a reservation if you’re planning to visit in high season. Enjoy the seafront restaurants (and, of course, fresh-caught fish specialties) and many tapas bars in this charming Catalan town.

A spot of white in the turquoise waters of the Aegean Sea, the island of Naxos is a unique blend of ancient ruins and beach culture. The largest of the Cycladic Islands, Naxos is the childhood home of none other than Zeus, king of the gods. Upon arrival in Naxos, hike over a causeway to Palatia, where the Portara, a stone gateway to an ancient temple that no longer exists, stands alone, the symbol of the island. At sunset, the views of the island, and the sea beyond, are breathtaking.

This resort town, with its great beaches, has a bit of a Spring Break atmosphere (the parties start in the late afternoon and go all night). If dancing in a bikini is not your thing, though, no worries—you can explore a mediaeval monastery or enjoy cruises on the lovely blue water. Families will want to visit Water World, the biggest theme waterpark in Europe.

Religious pilgrims have been travelling to Jerusalem for centuries, yet you don’t have to share their zeal in order to appreciate this city’s profound cultural and historical significance. Plan on seeing the major sights, but also leave plenty of time to walk through the streets and simply immerse yourself in the daily life of such an ancient and revered place.

The Dominican Republic lies in the same waters as Cuba and Puerto Rico, taking up the eastern two-thirds of the island it shares with Haiti. Offering a lush interior with a mix of caves, Victorian gingerbread houses and the lore of pirates, plus 900 miles of coastline along its brim, island highlights include riding a cable car up Mount Isabel de Torres and basking on stunning Saona Island. Oh, and did we mention the D.R. is family-friendly, has just about perfect weather and is affordable?

If you’re a history buff and a die-hard foodie, Chicago’s your kind of town. Take an architectural-history walking tour, then dine at Alinea (the most celebrated molecular-gastronomy restaurant in the U.S.). And don’t miss the Museum of Science and Industry, the biggest science museum in the Western Hemisphere.

Florida's Southwest Gulf Coast contains a constellation of enticing coastal gems. Stunning beaches, including Fort Myers Beach, Tigertail Beach and Pensacola Beach, fringe the Gulf, down the I-75 from Tampa to Naples. Sanibel Island's shells attracts thousands. Cape Coral's waters are paradise for fly-fishing. Golfers adore spectacular courses in Marco Island and Naples. Glorious sunny days and deliciously warm turquoise waters beckon in this often overlooked corner of the Sunshine State.