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Three Sisters Cafe

6223 Guilford Ave, Indianapolis, IN 46220-1928
+1 317-257-5556
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  • Excellent53%
  • Very good30%
  • Average10%
  • Poor3%
  • Terrible4%
Travellers talk about
“brunch” (17 reviews)
“egg scramble” (7 reviews)
“sandwich” (25 reviews)
Open Now
8:00 AM - 9:00 PM Hours
American, Cafe, Deli, Vegetarian Friendly, Gluten Free Options, Vegan Options
$$ - $$$
6223 Guilford Ave, Indianapolis, IN 46220-1928
All Details
Write a ReviewReviews (214)
Traveller rating
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Time of year

1 - 10 of 214 reviews

Reviewed 4 days ago via mobile

Service with big smiles. Huge portions. Groovy grains with five(!!) additions was delicious. My small lemon corn cake with lemon curd and berries side was a bargain.

Thank DebbieGMadison_CT
Reviewed 1 week ago via mobile

It was the most unique breakfast plates i have had. The johnny cakes with blueberry and the three different toppings. I have never seen my wife of 40 years eat cornbread but she ate the pancakes. Staff were great. We sat on the porch and...More

Thank Thomas C
Reviewed 3 weeks ago via mobile

Complete food junkie and this is probably the best breakfast we have had while traveling. My wife had the famous lemon corncakes which are an absolute must! The mocha was a great addition as well. I had the omelet of the day, which was chorizo,...More

Thank Jonnyh2005
Reviewed 8 April 2018 via mobile

We went for brunch. Getting there before 11:00 is a good idea, minimizing the wait. The food was good. The baked goods are spectacular. I had eggs Florentine, it was fine but the bacon and sausage is delicious.

Thank themac3s
Reviewed 31 March 2018

The food at this restaurant is very good, as mentioned in the title. However, the choice is limited to basically pizzas and sandwiches, with a few other options... so make sure this is what you are looking for before going there.

Thank Léa F
Reviewed 22 March 2018

Over the years we have taken our granddaughter to Three Sisters Cafe but this is our first visit to their new location. It has the same charm and good service and has an even larger selection of very good food choices. It was very crowded...More

Thank michindtx
Reviewed 19 March 2018

If you want a bohemian vibe, unshaven hippies to wait on you, an old restaurant with a dirty feel and mediocre food, then this is your place. Not for us. Reuben was marginal at best. Did not care for the turkey sandwich or the potato...More

Thank meadrooney
Reviewed 18 February 2018 via mobile

Cute place. Super busy on a Sunday at noon. I was solo and was able to get seated immediately. My seat was a tiny, old school desk in what looked to be the upstairs attic. It was light filled and there were others very close...More

Thank T1632DSjuliew
Reviewed 20 January 2018

Came here on a cold Saturday morning and were promptly seated. This seems like a place where the owners know a few of their customers, as people from the kitchen kept coming out to chat with others at tables around us. We were greeted promptly...More

Thank Innerhousewife
Reviewed 19 January 2018

While traveling we try to find local and unique eateries that offer up good food and Three Sisters Cafe delivered. The food was plentiful and excellent and our server was efficient and kind which made for a very pleasant experience. Absolutely worth driving a bit...More

Thank MichiganTess
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Ask a question
Questions & Answers
12 February 2016|
AnswerShow all 2 answers
Response from Michael V | Reviewed this property |
I don't think they serve any alcohol. But I don't drink that early, so I'm not absolutely sure.
candy w
28 January 2016|
AnswerShow all 3 answers
Response from Anita D | Reviewed this property |
I do not know about gluten Free foods there. But the staff is very accommodating and helpful and I am sure would be able to make something you can eat.
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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
Breakfast, Lunch, Brunch, Dinner
Restaurant features
Takeout, Outdoor Seating, Seating, Waitstaff, Parking Available, Highchairs Available, Wheelchair Accessible
Good for
Child-friendly, Local cuisine, Kids
Open Hours
8:00 AM - 4:00 PM
8:00 AM - 9:00 PM
8:00 AM - 9:00 PM
8:00 AM - 9:00 PM
8:00 AM - 9:00 PM
8:00 AM - 9:00 PM
8:00 AM - 9:00 PM
Location and Contact Information
  • Address: 6223 Guilford Ave, Indianapolis, IN 46220-1928
  • Location: United States  >  Indiana (IN)  >  Indianapolis
  • Phone Number: +1 317-257-5556
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