We noticed that you're using an unsupported browser. The TripAdvisor website may not display properly.We support the following browsers:
Windows: Internet Explorer, Mozilla Firefox, Google Chrome. Mac: Safari.

Panacea Coffeehouse Cafe & Roastery

66 Commerce St, Waynesville, NC 28786-5738
+1 828-452-6200
Map updates are paused. Zoom in to see updated info.
Reset zoom
Updating Map...
  • Excellent63%
  • Very good29%
  • Average6%
  • Poor1%
  • Terrible1%
Travellers talk about
“panini” (16 reviews)
“sandwiches” (33 reviews)
“lox” (4 reviews)
Open Now
7:00 AM - 5:00 PMAll hours
American, Cafe, International, Healthy, Vegetarian Friendly, Vegan Options, Gluten Free Options
$$ - $$$
66 Commerce St, Waynesville, NC 28786-5738
All Details
Write a Review
Reviews (215)
Traveller rating
Traveller type
Time of year

1 - 10 of 215 reviews

Reviewed 1 week ago

Lovely cafe’ with good coffee but the quich was microwaved and chewy. Didn’t try the pastries but will not return.

Thank Tami O
Reviewed 2 weeks ago

The Coffeehouse is nestled in the unsuspecting warehouse area of Waynesville next to the train tracks. Panacea completely gutted the warehouse into a neat, hip, coffee roastery with great food and coffee. The back porch area sits right on a beautiful creek and is lit...More

Thank pittmanarizona
Reviewed 2 weeks ago

We had become regulars at Panacea. I repeatedly order their yogurt and fruit plus one of their tasty blueberry muffins and ice tea. My husband usually has the" Red headed step child," and he is hard to please. The funky, laid-back venue borders the railroad...More

Thank Poogan
Reviewed 4 weeks ago

Our favorite lunch place in Waynesville. Can sit outside besides a small creek and enjoy the scenery while you have an enjoyable lunch. Some of the best sandwiches in town.

Thank Stephen P
Reviewed 8 September 2017 via mobile

This is a great place. Nice friendly atmosphere. Great cozy seats, a place where you take 5 and relax. So glad we found this place, after a recommendation from a local nurse. Will definitely be returning. You should give it a try.

Thank simplynoname
Reviewed 6 September 2017 via mobile

That's the definition of the word Panacea...a cure all or something that makes the situation better... You can smell the beans roasting as you drive by this unique Frog Level Location. It's an old warehouse. Out front are the rail road tracks and outback is...More

Thank Duchess1031
Reviewed 28 August 2017 via mobile

Set in an old warehouse along the bank of a small river, this place has the look and feel of an old coffeehouse, with a quaint and rustic charm that makes you want to spend the afternoon here. My wife and I ordered coffee, while...More

Thank ERFSU82
Reviewed 27 August 2017

Stopped in for a latte while shopping at Frog Level recently. The atmosphere is great. Latte and chocolate chip cookie were both excellent. Cheerful service. Wish it had been lunch time, as the selections looked good. Will make sure to try them next visit.

Thank deejaye60
Reviewed 18 August 2017 via mobile

Great place to have breakfast or lunch. I had the quiche dishes on two separate days and my wife had the panini sandwiches. On both days they were great.The fresh in house roasted is great. Smooth and bold for the coffee I chose. We were...More

Thank Bruce N
Reviewed 17 August 2017 via mobile

A wonderful large coffeehouse with good food. I just sat for hours, worked and enjoyed the view, my cappuccino and frilled cheese! A terrific spit and wonderful service.

Thank Denise K
Nearby Restaurants
Chef's Table
572 reviews
.49 km away
The Sweet Onion
1,245 reviews
.41 km away
Frogs Leap Public House
624 reviews
.46 km away
Smoky Mountain Sub Shop
156 reviews
.43 km away
Nearby Attractions
The Mahogany House Art Gallery & Studios
33 reviews
.15 km away
Cedar Hill Studio & Gallery
14 reviews
.70 km away
Love Lane Flower Farm
5 reviews
.33 km away
A Cat In The Attic Treasures & Treats Antiques Towne Square
12 reviews
.52 km away
Questions & Answers
Get quick answers from Panacea Coffeehouse Cafe & Roastery staff and past visitors.
Note: your question will be posted publicly on the Questions & Answers page.
Posting guidelines
Improve this listing

Restaurant Details

Rating summary
  • Food
  • Value
Average prices
US$5 - US$12
Breakfast, Lunch, Brunch
Restaurant features
Takeout, Outdoor Seating, Seating, Wheelchair Accessible, Free Wifi
Good for
Business meetings, Kids, Child-friendly
Open Hours
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
8:00 AM - 5:00 PM
Location and Contact Information
  • Address: 66 Commerce St, Waynesville, NC 28786-5738
  • Location: United States  >  North Carolina (NC)  >  North Carolina Mountains  >  Waynesville
  • Phone Number: +1 828-452-6200
  • E-mail
Is This Your TripAdvisor Listing?
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more. Claim Your Listing