Thanks so much!
Sorry but I think you risk to have a big hassle to reach Florence, other parts of Tuscany and Rome, neglecting what you'll have close at hand. Ten days are not an enormous amount of time. A place like Collepepe sounds much more suitable for relax than for jumping into the car every early morning to rush here and there. And are you aware of all that Umbria can offer, mostly without the touristyness which affects Rome, Florence and other places in Tuscany?
Thanks for responding. If you could make suggestions to stay close and away from the tourist traps, I would really appreciate the info. As of now, our 10 days are completely open. Again, thanks for sharing!