I had the opportunity to visit Fort Wayne last month, part of my Midwest Final Farewell tour before I move out west! I was impressed with the amount of activities to do, and the summer calendar full of activities.
I would have preferred to stay downtown, but getting around was manageable. I loved Parkview Field - so much to do in addition to watching baseball. Also got out for a paddle on the rivers, took the dog to Bicentennial Woods and Fox Island, and got a backstage tour of the Arts United Center.
I would highly recommend Fort Wayne as a Midwest weekend destination!