We had booked the half day tour of Milan that included the Duomo, La Scala and the last supper. The meeting point was easy to get to, the staff there were not that helpful at all.
The tour it self was interesting and the guide was very knowledgeable, we also walked through the galleria. The Duomo is spectacular, even though you do tend to visit so many churches in Europe this is not to be missed.
The Last Supper is amazing, it is a timed visit, you only have 15 minutes in the room, and you can take photos. The bus then drops you off at the meeting point.
As with most of these tours you skip the queue! and remember shoulders and knees are to be covered fro both men and women.